GREEN SYNTHESIS OF SILVER NANOPARTICLES FROM AQUEOUS EXTRACT OF UNRIPE PAWPAW PEEL AND ITS ANTIMICROBIAL AND ANTIOXIDANT PROPERTY

Olugbemi, T. I. (2019) GREEN SYNTHESIS OF SILVER NANOPARTICLES FROM AQUEOUS EXTRACT OF UNRIPE PAWPAW PEEL AND ITS ANTIMICROBIAL AND ANTIOXIDANT PROPERTY. FEPI-JOPAS, 1 (1). pp. 203-209. ISSN 2714-2531

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Abstract

Green synthesis is considered an alternative approach for synthesizing silver nanoparticles (AgNPs) as it is ecofriendly and cost effective.The present work investigated the synthesis of silver nanoparticles using unripe pawpaw peel extract (UPPE) and assayed for its antimicrobial and antioxidant properties. Method:AgNps were synthesized from 1 mM AgNO3 solution through the aqueous extract of unripe pawpaw peel. Primary characterization of synthesized silver nanoparticles was carried out using UV-visible spectroscopy. The antimicrobial and antioxidant activities of the synthesized AgNps was investigated using standard methods of analysis. The colourless reaction mixture of AgNO3 solution and aqueous extract of unripe pawpaw peel turned brown and displayed UV-visible spectra of 450nm which is characteristic of silver nanoparticles . The present study revealed that silver nanoparticles prepared from unripe pawpaw peel extract showed greater antimicrobial activity against Escherichia coli, Staphylococcus aureus, Aspergillus niger which are common food related pathogens than Gentamycin. The antioxidant assay also revealed that maximum scavenging activity against DPPH was exhibited by the synthensized nanoparticles which showed a concentration-dependent scavenging activity with IC50 of 54.78 μg/ml when compared to the standard with IC50: 59.93 μg/ml. Ascorbic acid exhibited the highest scavenging activity against ABTS with (IC50: 50.95 μg/ml), followed by the synthensized AgNps (IC50: 52.20 μg/ml).optimization of this green synthesis would support the production of agnps with great therapeutic potentials.

Item Type:	Article
Subjects:	Q Science > Q Science (General) Q Science > QD Chemistry
Divisions:	Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User:	Mr Taiwo Egbeyemi
Date Deposited:	11 May 2020 19:13
Last Modified:	11 May 2020 19:13
URI:	http://eprints.federalpolyilaro.edu.ng/id/eprint/73

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