OCHI, I.O. and OGAH, E. and LONGBAP, B.D. and Abiaziem, C. V and TABE, N.T. (2015) PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL SCREENING OF DRIED ROOT EXTRACTS OF ALCHORNEA CORDIFOLIA. Ewemen Journal of Microbial Research, 1 (1). pp. 25-30. ISSN 2488-9148
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Abstract
The use of plants as herbs for the treatment of human ailments is a common practice in all parts of the world. This has in no doubt contributed immensely towards the growth and rapid development of phytomedicines. Alchornea cordifolia has been a source of several novel and bioactive natural compounds. Traditionally, it is used for the treatment of several ailments. The dried roots were extracted with nhexane, n-butanol and 95% ethanol. The crude extracts obtained were investigated for chemical and biological activities. Qualitative Phytochemical screening of the dried root extracts obtained by maceration confirmed the presence of various phytochemicals. The crude extracts were also investigated for biological activity and the results showed high concentration dependent activity against S. aureus, B. subtilis, P. aeruginosa and C. albicans with zone of inhibition ranging from 10-23 mm at concentrations ranging from 12.5 to 100 mg/mL. The 95% ethanolic extract demonstrated the highest activity against the test organisms. The aim of the present study is to evaluate the chemical and biological activities of the bioactive constituents of A. cordifolia dried root extracts. The present analysis suggests that A. cordifolia possesses remarkable Phytochemical and antibacterial property.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > Q Science (General) |
| Divisions: | Faculty of Engineering, Science and Mathematics > School of Chemistry |
| Depositing User: | Mr Taiwo Egbeyemi |
| Date Deposited: | 03 Jun 2020 19:43 |
| Last Modified: | 03 Jun 2020 19:43 |
| URI: | http://eprints.federalpolyilaro.edu.ng/id/eprint/340 |
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