Akanbi, Olumuyiwa O. and Agbolade, Olumuyiwa A and Shomoye, Idowu A. (2017) PHYSICAL AND MONTE CARLOS SIMULATION OF CONTINUOUS TIME MODEL OF SICKLE CELL ANAEMIA. In: SPASCIT, 4th – 7th December, 2017., Federal Polytechnic Ilaro, Ogun State.
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Abstract
Sickle Cell Disease (SCD) is a potentially devastating condition that is caused by an autosomal recessive inherited hemoglobinopathy which results in the vaso-occlusive phenomena and hemolysis. Sickle Cell anaemia is the most common form of Sickle Cell Disease. As such, this paper provides an insight on the mathematical transmission dynamics of Sickle Cell Anaemia and develops a physical realistic model. A female dominant renewal equation of birth dynamics was developed for both populations with genotype screening and without genotype screening. By Hardy-Weinberg equation we obtained the frequency of different genotype groups for the physical simulation. Thereafter, Monte Carlos simulation techniques was carried out to justify our position on the renewal equation. We observed that accessible curative measure still stands the only solution to the menace of Sickle Cell Anaemia in our society.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Subjects: | Q Science > QA Mathematics |
| Divisions: | Faculty of Engineering, Science and Mathematics > School of Mathematics |
| Depositing User: | Mr Taiwo Egbeyemi |
| Date Deposited: | 28 Jun 2020 20:05 |
| Last Modified: | 28 Jun 2020 20:05 |
| URI: | http://eprints.federalpolyilaro.edu.ng/id/eprint/773 |
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