Biosynthesis of Silver nanoparticles from aqueous extract of unripe plantain peel and its antibacterial assay: a novel biological approach

OLUGBEMI, Iyanuoluwa Temitayo (2019) Biosynthesis of Silver nanoparticles from aqueous extract of unripe plantain peel and its antibacterial assay: a novel biological approach. International Journal of Pharmaceutical Science and Health, 5 (9). pp. 9-16. ISSN 2249 – 5738

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Abstract

Biological method of silver nanoparticles synthesis has now become a novel method to physical and chemical approaches. In the present study, silver nanoparticles (AgNPs) were synthesized from unripe plantain peel extract (UPPE).This study examined the aqueous extracts of unripe plantain peel (sundried and Fresh) for the synthesis of Silver nanoparticles and compared their possible antibacterial potency with standard antibiotics: Ofloxacin and Ampicillin against human pathogens such as Escherichia coli and Salmonella typhi. The silver nanoparticles were prepared by reducing AgNO3 with unripe plantain peel extract which act as natural reducing agent. The antimicrobial assay was carried out using Mueller Hinton Agar well. Synthesis of AgNPs was confirmed by UV-Visible spectroscopy and plasmon peak maxima was observed at 425nm and 475nm for sundried and Fresh samples (SD-AgNPs and FR-AgNPs) respectively at 24h interval. The antibacterial assay of the samples revealed higher antimicrobial activity for SD-AgNPs against Escherichia coli than Ofloxacin while FR-AgNPs showed antibacterial activity against E. coli and ampicillin showed none. SD-AgNPs showed a synergetic effect with the standard antibiotics (ofloxacin) against Salmonella typhi. Hence, the antimicrobial activities of the AgNPs synthesized from aqueous extract of unripe plantain could be utilized in the management of infectious diseases due to their antimicrobial potency.

Item Type:	Article
Subjects:	Q Science > Q Science (General) Q Science > QD Chemistry R Medicine > R Medicine (General)
Divisions:	Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User:	Mr Taiwo Egbeyemi
Date Deposited:	11 May 2020 19:12
Last Modified:	11 May 2020 19:12
URI:	http://eprints.federalpolyilaro.edu.ng/id/eprint/72

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