EFFECTS OF FOLIC ACID SUPPLEMENTATION ON SERUM LIPID PROFILE IN MALE ALBINO RATS

Bankole, Olukayode Olusola and Omoyeni, Oluwatobi Cynthia (2018) EFFECTS OF FOLIC ACID SUPPLEMENTATION ON SERUM LIPID PROFILE IN MALE ALBINO RATS. In: Crawford University Science Conference and Fair (CUSCAF 2018), 23rd – 25th October, 2018, Crawford University.

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Abstract

Cardiovascular disease (CVD) are caused by disorder of the heart and blood vessels. Risk factors may include elevated serum levels of total cholesterol, triglyceride, low density lipoprotein and reduced serum concentration of high density lipoprotein among other things. Different reports have revealed interfaces between supplementation with vitamin B complex and decrease in oxidative stress and inflammation, which are related with cardiovascular disorders. This study is therefore designed to assess the effects of folic acid in the regulation of serum lipids such as total cholesterol, phospholipids, triglycerides, and high density lipoprotein cholesterol (HDL-C). Serum lipid profile were assayed for using standard procedures. Results showed that serum total cholesterol and triglyceride were significantly reduced (p≤0.05) in rats placed on folic acid supplements compared with control group. Serum phospholipids and high density lipoprotein cholesterol were significantly elevated (p≤0.05) in rats placed on vitamin B6 supplements when compared with control group. The data showed anti-hyperlipidaemic effects of folic acid supplementation in rats.

Item Type:	Conference or Workshop Item (Paper)
Subjects:	Q Science > Q Science (General) Q Science > QD Chemistry
Divisions:	Faculty of Engineering, Science and Mathematics > School of Chemistry
Depositing User:	Mr Taiwo Egbeyemi
Date Deposited:	11 May 2020 20:10
Last Modified:	11 May 2020 20:10
URI:	http://eprints.federalpolyilaro.edu.ng/id/eprint/102

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